Role of male factor in early recurrent embryo loss: do antioxidants have any effect?

CONCLUSIONS: All couples whose male partners accepted antioxidant supplementation achieved a successful pregnancy. This study demonstrates the benefits of an increased intake of antioxidant-rich food or antioxidant supplements by men who show high levels of sperm DNA fragmentation or lipid peroxidation, which could result in an improvement in gestational outcomes in couples with history of recurrent pregnancy loss (RPL).

Low folate in seminal plasma is associated with increased sperm DNA damage

CONCLUSION(S): Low concentrations of folate (folic acid, B9) in seminal plasma may be detrimental for sperm DNA stability, and total homocysteine (B6, 9, 12) correlated with sperm count.

Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial.

CONCLUSION(S): 74% increase in total normal sperm count after combined zinc sulfate (66mg) and folic acid (5mg) treatment for 26 weeks (6 months) in both subfertile and fertile men.

Semen quality in relation to antioxidant intake in a healthy male population

In a population of healthy young men, carotenoid intake was associated with higher sperm motility and, in the case of lycopene, better sperm morphology. Our data suggest that dietary carotenoids may have a positive impact on semen quality.

To assess the relationship between dietary antioxidant intake and semen quality in young healthy males.

Cross-sectional study.

University and college campuses in the Rochester, New York, area.

One hundred eighty-nine university-aged men.

Paternal diet-induced obesity impairs embryo development and implantation in the mouse

Conclusion(s): This study demonstrates that paternal obesity impairs preimplantation embryo development and implantation but does not influence gross fetal or placental morphology. It highlights the important contribution that paternal health and lifestyle choices have for achieving a viable pregnancy.

To use a rodent model of male diet-induced obesity (DIO) to examine resultant preimplantation embryo development and implantation rate, as well as fetal and placental growth.

Experimental animal study.

Effects of L-Carnitine and Coenzyme Q10 on Impaired Spermatogenesis

Conclusions: treatment with L-carnitine and Coenzyme Q10 significantly increased total antioxidant, LH and testosterone levels. Treatment with L-carnitine and Coenzyme Q10 also improved semen parameters and organs weight. L-carnitine and Coenzyme Q10 could protect spermatogenesis.

Food intake and its relationship with semen quality: a case-control study

CONCLUSION(S): Frequent intake of lipophilic foods like meat products or milk may negatively affect semen quality in humans, whereas some fruits or vegetables may maintain or improve semen quality.

Subscribe to NUTRITION & SPERM